Myasthenia gravis is an autoimmune disease linked to blockage of motor endplate receptors by anti-acetylcholine receptor antibodies or other types of antibodies inducing dysfunction of neuromuscular transmission: this is postsynaptic block.
The responsibility of the thymus is important: the acetylcholine receptors of the myoid cells of the thymus lead to the stimulation of antibodies against the neuomuscular junction receptors; the thymus is a source of helper T lymphocytes stimulating the production of these antibodies by B lymphocytes.
It can occur at any age, but most often affects adults.
Between the ages of 20 and 40, it is more common in women, while above 60, myasthenia predominates in men.
The score ranges from 0 to 100. The lower the score, the higher the severity. 100 is therefore a normal score, and 0 is the maximum quantifiable severity.